A synthetic bola-amphiphile
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CAY10679

Item No. 9001475

Technical Information
Formal Name
1,1'-(1,8-dioxo-1,8-octanediyl)bis[glycyl-glycine
CAS Number
143673-93-2
Synonyms
  • N,N'-bis(glycyl-glycine)-hexane-1,6-Dicarboxyamide
Molecular Formula
C16H26N4O8
Formula Weight
Purity
≥95%
A crystalline solid
DMSO: 1 mg/ml (warmed)
SMILES
O=C(O)CNC(CNC(CCCCCCC(NCC(NCC(O)=O)=O)=O)=O)=O
InChi Code
InChI=1S/C16H26N4O8/c21-11(17-7-13(23)19-9-15(25)26)5-3-1-2-4-6-12(22)18-8-14(24)20-10-16(27)28/h1-10H2,(H,17,21)(H,18,22)(H,19,23)(H,20,24)(H,25,26)(H,27,28)
InChi Key
LDCHADQWAFSFRX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    CAY10679 is an anionic oligopeptide-based bola-amphiphile that contains a hexane moiety flanked by a glycylglycine group at each end, which creates distinct hydrophilic and hydrophobic regions.1 The microtube self-assembling properties of this amphiphilic peptide have been studied in aqueous acidic solution.2 Bola-amphiphiles are of interest in the construction of nanotubes, nanovesicles, nanowires, nanocarriers for drug delivery, and other applications of bionanotechnology.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Santoso, S.S., Vauthey, S., and Zhang, S. Structures, function and applications of amphiphilic peptides. Curr. Opin. Colloid In. 7, 262-266 (2013).

    2. Naidoo, V.B., and Rautenbach, M. Bidirectional solid phase synthesis of a model oligoglycine bolaamphiphile and purification by rapid self-assembly. J. Pept. Sci. 18(5), 317-325 (2012).