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Unlabeled Version(s)
11737Benocyclidine
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Benocyclidine-d10

Item No. 9001493

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • BCP-d10
  • Benzothiophenylcyclohexylpiperidine-d10
  • BTCP-d10
  • GK 13-d10
Technical Information
Formal Name
1-(1-benzo[b]thien-2-ylcyclohexyl)-2,2,3,3,4,4,5,5,6,6-d10-piperidine
Molecular Formula
C19H15D10NS
Formula Weight
309.5
Purity
≥99% deuterated forms (d1-d10)
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlEthanol: 2 mg/ml
λmax
229, 270, 300 nm
SMILES
[2H]C(C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H])([2H])N1C2(C3=CC4=C(C=CC=C4)S3)CCCCC2
InChi Code
InChI=1S/C19H25NS/c1-5-11-19(12-6-1,20-13-7-2-8-14-20)18-15-16-9-3-4-10-17(16)21-18/h3-4,9-10,15H,1-2,5-8,11-14H2/i2D2,7D2,8D2,13D2,14D2
InChi Key
RGSVXQJPSWZXOP-PGAPGPTOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Benocyclidine-d10 (BCP-d10) contains ten deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, and 6' positions. It is intended for use as an internal standard for the quantification of BCP (Item No. 11737) by GC- or LC-mass spectrometry. BCP is a derivative of phencyclidine with a benzothiophenyl group instead of a phenyl ring. It acts as a potent and selective dopamine reuptake inhibitor (IC50 = 8 nM) with negligible affinity for the NMDA receptor-linked phencyclidine receptor (K0.5 = 6 μM).1,2 BCP has been used to label the dopamine transporter in the mouse brain.3 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vignon, J., Pinet, V., Cerruti, C., et al. [3H]N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine ([3H]BTCP): A new phencyclidine analog selective for the dopamine uptake complex. Eur. J. Pharmacol. 148(3), 427-436 (1988).

    2. Chaudieu, I., Vignon, J., Chicheportiche, M., et al. Role of the aromatic group in the inhibition of phencyclidine binding and dopamine uptake by PCP analogs. Pharmacol. Biochem. Behav. 32(3), 699-705 (1989).

    3. Maurice, T., Vignon, J., Kamenka, J.M., et al. In vivo labelling of the mouse dopamine uptake complex with the phencyclidine derivative [3H]BTCP. Neurosci. Lett. 101(2), 234-238 (1989).