An antioxidant and free radical scavenger
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Salvianolic Acid B

Item No. 9001577

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylic acid (2S,3S)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester
CAS Number
121521-90-2
Synonyms
  • Lithospermate B
Molecular Formula
C36H30O16
Formula Weight
718.6
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 1 mg/ml
SMILES
OC1=CC=C(C[C@H](C(O)=O)OC(/C=C/C2=CC=C(O)C3=C2[C@H](C(O[C@@H](C(O)=O)CC4=CC(O)=C(O)C=C4)=O)[C@@H](C5=CC(O)=C(O)C=C5)O3)=O)C=C1O
InChi Code
InChI=1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,2
InChi Key
SNKFFCBZYFGCQN-VWUOOIFGSA-N
Origin
Plant/Salviae Miltiorrhizae Radix et Rhizoma
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $36

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    5 mg

    $110

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    10 mg

    $153

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    25 mg

    $336

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    Cayman Chemical
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    Product Description

    Salvianolic acid B is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties.1,2 It has been reported to reduce leukocyte-endothelial adherence, inhibit inflammation and metalloproteinase expression from aortic smooth muscle cells, and regulate immune function and certain intracellular kinase associated signaling pathways by competitively inhibiting the protein-protein interactions mediated by key binding domains.1,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ho, J.H.C., and Hong, C.Y. Salvianolic acids: Small compounds with multiple mechanisms for cardiovascular protection. J. Biomed. Sci. 18(1), 30 (2011).

    2. Liu, G.T., Zhang, T.M., Wang, B.e., et al. Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes. Biochem. Pharmacol. 43(2), 147-152 (1992).

    3. Zhao, Y., Guo, Y., and Gu, X. Salvianolic Acid B, a potential chemopreventive agent, for head and neck squamous cell cancer. J. Oncol. 534548 (2011).