A probe for 12(S)-HETE activity
Related Products
Unmodified Version(s)
3457012(S)-HETE
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

12(S)-HETE-19,20-alkyne

Item No. 9001937

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(S,5Z,8Z,10E,14Z)-12-hydroxyicosa-5,8,10,14-tetraen-19-ynoic acid
Synonyms
  • Click Tag™ 12(S)-HETE-19,20-alkyne
  • 12(S)-Hydroxyeicosatetraenoic Acid-19,20-alkyne
Molecular Formula
C20H28O3
Formula Weight
316.4
Purity
≥97%
Formulation (Request formulation change)
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
0.1 M Na2CO3: 2 mg/mlDMF: MiscibleDMSO: MiscibleEthanol: MisciblePBS (pH 7.2): 0.5 mg/ml
λmax
236 nm
SMILES
C#CCCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(O)=O
InChi Code
InChI=1S/C20H28O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h1,7-11,13-14,17,19,21H,3-6,12,15-16,18H2,(H,22,23)/b9-7-,11-8-,13-10-,17-14+/t19-/m0/s1
InChi Key
YNUPBNFKEDXDHP-LQWMCKPYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 µg

    $179

    Add

    50 µg

    $337

    Add

    100 µg

    $636

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    12(S)-HETE-19,20-alkyne is a form of 12(S)-HETE with an ω-terminal alkyne. The terminal alkyne group can be used in click chemistry linking reactions, to tag 12(S)-HETE with fluorescent or biotinylated labels for analysis of its metabolism and biological activity.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kolb, H.C., and Sharpless, K.B. The growing impact of click chemistry on drug discovery. Drug Discov. Today 8(24), 1128-1137 (2003).

    2. Lutz, J.-F., and Zarafshani, Z. Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide-alkyne "click" chemistry. Adv. Drug Deliv. Rev. 60(9), 958-970 (2008).