A PEGylated form of trimethoprim
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Trimethoprim-PEG3-amine (trifluoroacetate salt)

Item No. 9002107

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-2-(4-((2,6-diaminopyrimidin-4-yl)methyl)-2,6-dimethoxyphenoxy)acetamide tris(2,2,2-trifluoroacetate)
Molecular Formula
C23H36N6O7 • 3CF3COOH
Formula Weight
850.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 15 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
210 nm
SMILES
COC1=C(OCC(NCCOCCOCCOCCN)=O)C(OC)=CC(CC2=CC(N)=NC(N)=N2)=C1.FC(F)(C(O)=O)F.FC(F)(C(O)=O)F.FC(F)(C(O)=O)F
InChi Code
InChI=1S/C23H36N6O7.3C2HF3O2/c1-31-18-12-16(11-17-14-20(25)29-23(26)28-17)13-19(32-2)22(18)36-15-21(30)27-4-6-34-8-10-35-9-7-33-5-3-24;3*3-2(4,5)1(6)7/h12-14H,3-11,15,24H2,1-2H3,(H,27,30)(H4,25,26,28,29);3*(H,6,7)
InChi Key
MVIXUVNYEFTCGL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 µg

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    Cayman Chemical
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    Product Description

    Trimethoprim-PEG3-amine is a conjugated form of trimethoprim linked with polyethylene glycol (PEG) amine. The addition of PEG to drugs can provide greater solubility, longer duration of exposure, and the potential to overcome resistance associated with the drug.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zamboni, W.C. Concept and clinical evaluation of carrier-mediated anticancer agents. Oncologist 13(3), 248-260 (2008).