A synthetic steroid and inhibitor of estrogen 2-hydroxylase
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2-bromo 17β-Estradiol

Item No. 9002145

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-bromo-estra-1,3,5(10)-triene-3,17β-diol
CAS Number
15833-07-5
Synonyms
  • 2-bromo E2
  • 2-bromo β-Estradiol
  • 2-bromo Estradiol
  • NSC 105460
  • 2-bromo 17β-Oestradiol
Molecular Formula
C18H23BrO2
Formula Weight
351.3
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleMethanol: Soluble
SMILES
C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC(Br)=C(O)C=C4CC3
InChi Code
InChI=1S/C18H23BrO2/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-16(20)15(19)9-13(10)11/h8-9,11-12,14,17,20-21H,2-7H2,1H3/t11-,12+,14-,17-,18-/m0/s1
InChi Key
SORISAYAZBCIQH-XSSYPUMDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $32

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    10 mg

    $61

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    25 mg

    $141

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    50 mg

    $264

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    Product Description

    2-bromo 17β-Estradiol is a synthetic steroid and an inhibitor of estrogen 2-hydroxylase.1 It inhibits estrogen 2-hydroxylase in rat liver microsomes when used at concentrations of 50 and 100 µM. 2-bromo 17β-Estradiol (5 mg/kg) prevents estrogen-induced inhibition of apomorphine-induced climbing behavior in mice.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Brueggemeier, R.W. Inhibition of estrogen 2-hydroxylase. J. Steroid. Biochem. 19(5), 1683-1685 (1983).

    2. Fung, Y.K., Stevens, J.M., Palmer, C.W., Jr., et al. Inhibition by bromoestrogens of the effects of estradiol on apomorphine-induced climbing behavior. Steroids 49(4-5), 287-294 (1987).