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4-Chloromethamphetamine (hydrochloride)

Item No. 9002185

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 4-CMA
  • p-CMA
  • para-CMA
  • Ro 4-6861
Technical Information
Formal Name
4-chloro-N,α-dimethyl-benzeneethanamine, monohydrochloride
CAS Number
30572-91-9
Molecular Formula
C10H14ClN • HCl
Formula Weight
220.1
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlMethanol: 1 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
221 nm
SMILES
CC(NC)CC1=CC=C(Cl)C=C1.Cl
InChi Code
InChI=1S/C10H14ClN.ClH/c1-8(12-2)7-9-3-5-10(11)6-4-9;/h3-6,8,12H,7H2,1-2H3;1H
InChi Key
HXTOYUVXDREQSD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    Product Description

    4-Chloromethamphetamine is a halogenated analog of methamphetamine. In vivo, it is converted to 4-chloroamphetamine (Item No. 9001856), which causes rapid depletion of neurological serotonin within hours after injection.1,2 4-Chloroampetamine is highly and selectively neurotoxic, targeting serotonergic neurons.1,2 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fuller, R.W., Baker, J.C., Perry, K.W., et al. Comparison of 4-chloro-, 4-bromo- and 4-fluoroamphetamine in rats: Drug levels in brain and effects on brain serotonin metabolism. Neuropharmacology 14(10), 739-746 (1975).

    2. Harvey, J.A., McMaster, S.E., and Fuller, R.W. Comparison between the neurotoxic and serotonin-depleting effects of various halogenated derivatives of amphetamine in the rat. J. Pharmacol. Exp. Ther. 202(3), 581-589 (1977).