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N-Benzylpalmitamide is a long-chain fatty acid amide (macamide or macaene) isolated from the maca (L. meyenii) plant and is structurally related to cannabinoids.1 N-Benzylpalmitamide has been the most frequently isolated of the 19 macamides currently identified. While many macamides have been identified as potent inhibitors of fatty acid amide hydrolase (FAAH), N-benzylpalmitamide displays only moderate FAAH inhibitory activity (44% inhibition at 500 µM).1 Additionally, many members of this family demonstrate selective antiproliferative activity against diverse cancer cell lines.2
WARNING This product is not for human or veterinary use.
1. Macamides and their synthetic analogs: Evaluation of in vitro FAAH inhibition. Bioorg. Med. Chem. 21(17), 5188-5197 (2013).
2. Antiproliferative activity of synthetic fatty acid amides from renewable resources. Bioorg. Med. Chem. 23(2), 340-347 (2015).