A fluorescent derivative of fructose
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Product Categories

Product Type

Biochemicals
Labeling & Detection
Fluorescent Probes

Research Area

Cancer
Metabolism

Application

Fluorescence

NBD-Fructose

Item No. 9002314

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-deoxy-1-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-fructose
CAS Number
940961-04-6
Synonyms
  • 1-NBDF
  • 1-(7-nitro-1,2,3-benzadiazole)-Fructose
Molecular Formula
C12H14N4O8
Formula Weight
342.3
Purity
≥95% (sum of isomers)
Emission
538 nm
Excitation
472 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 30 mg/mlWater: 30 mg/ml
λmax
226, 330, 461 nm
SMILES
O=C([C@@H](O)[C@H](O)[C@H](O)CO)CNC1=CC=C([N+]([O-])=O)C2=NON=C21
InChi Code
InChI=1S/C12H14N4O8/c17-4-8(19)12(21)11(20)7(18)3-13-5-1-2-6(16(22)23)10-9(5)14-24-15-10/h1-2,8,11-13,17,19-21H,3-4H2/t8-,11-,12-/m1/s1
InChi Key
PYUWRKIMILVYHE-GGZOMVNGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

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    Product Description

    NBD-Fructose is a fluorescent derivative of fructose that is formed by coupling NBD-chloride with the amine group of amino fructose.1 It has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells. NBD-Fructose displays excitation/emission maxima of 472/538 nm, respectively.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Levi, J., Cheng, Z., Gheysens, O., et al. Fluorescent fructose derivatives from imaging breast cancer cells. Bioconjug. Chem. 18(3), 628-634 (2007).