An electron transport inhibitor in plants
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DNP-INT

Item No. 9003061

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(2,4-dinitrophenoxy)-3-iodo-4-methyl-1-(1-methylethyl)-5-nitro-benzene
CAS Number
69311-70-2
Molecular Formula
C16H14IN3O7
Formula Weight
487.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 5 mg/ml
λmax
280 nm
SMILES
CC1=C(I)C(OC2=CC=C([N+]([O-])=O)C=C2[N+]([O-])=O)=C(C(C)C)C=C1[N+]([O-])=O
InChi Code
InChI=1S/C16H14IN3O7/c1-8(2)11-7-12(19(23)24)9(3)15(17)16(11)27-14-5-4-10(18(21)22)6-13(14)20(25)26/h4-8H,1-3H3
InChi Key
JWEBDWJHYHAROA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $49

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    5 mg

    $213

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    10 mg

    $376

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    25 mg

    $820

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    Product Description

    DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).1 It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Barbagallo, R.P., Finazzi, G., and Forti, G. Effects of inhibitors on the activity of the cytochrome b6f complex: Evidence for the existence of two binding pockets in the lumenal site. Biochemistry 38(39), 12814-12821 (1999).

    2. Trebst, A., Wietoska, H., Draber, W., et al. The inhibition of photosynthetic electron flow in chloroplasts by the dinitrophenylether of bromo-or iodo-nitrothymol. Z. Naturforsch. C J. Biosci. 33(11-12), 919-927 (1978).

    3. Malkin, R. Interaction of stigmatellin and DNP-INT with the Rieske iron-sulfur center of the chloroplast cytochrome b6f complex. FEBS Lett. 208(2), 317-320 (1986).