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Lignoceric acid-d47 is intended for use as an internal standard for the quantification of lignoceric acid (Item No. 13353) by GC- or LC-MS. Lignoceric acid is a 24-carbon saturated (24:0) fatty acid. In mammals, it is synthesized during brain development and is found in cerebrosides.1 The deficient peroxisomal oxidation of very-long-chain fatty acids, including lignoceric acid, contributes to certain syndromes, including Zellweger cerebro-hepato-renal syndrome and X chromosome-linked adrenoleukodystrophy.2 Lignoceric acid is also a by-product of lignin production.
WARNING This product is not for human or veterinary use.
1. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-
2. Lignoceric acid is oxidized in the peroxisome: Implications for the Zellweger cerebro-