A sphingolipid
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C22 Galactosylceramide (d18:1/22:0)

Item No. 9003458

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-docosanamide
CAS Number
74645-25-3
Synonyms
  • N-Docosanoyl-β-D-Galactosylceramide
  • Galactosylceramide (d18:1/22:0)
  • GalCer(d18:1/22:0)
Molecular Formula
C46H89NO8
Formula Weight
784.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
SMILES
O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](OC[C@H](NC(CCCCCCCCCCCCCCCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC)[C@@H]1O
InChi Code
InChI=1S/C46H89NO8/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-24-26-28-30-32-34-36-42(50)47-39(38-54-46-45(53)44(52)43(51)41(37-48)55-46)40(49)35-33-31-29-27-25-23-16-14-12-10-8-6-4-2/h33,35,39-41,43-46,48-49,51-53H,3-32,34,36-38H2,1-2H3,(H,47,50)/b35-33+/t39-,40+,41+,43-,44-,45+,46+/m0/s1
InChi Key
YIGARKIIFOHVPF-YMBRMJIUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $597

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    Product Description

    C22 Galactosylceramide is a sphingolipid that has been found in the central nervous system.1,2 C22 Galactosylceramide levels are increased in the spinal cord, but not the brain or liver, of mice fed a methionine-restricted diet.1 C22 Galactosylceramide has been found in postmortem hippocampus from patients with Alzheimer's disease.2 As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 2138]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jové, M., Ayala, V., Ramírez-Núñez, O., et al. Specific lipidome signatures in central nervous system from methionine-restricted mice. J. Proteome Res. 12(6), 2679-2689 (2013).

    2. Hejazi, L., Wong, J.W.H., Cheng, D., et al. Mass and relative elution time profiling: Two-dimensional analysis of sphingolipids in Alzheimer’s disease brains. Biochem. J. 438(1), 165-175 (2011).