A derivative of remdesivir
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Product Type

Biochemicals

Research Area

Remdesivir isopropyl ester analog

Item No. 9003635

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(S)-hydroxyphenoxyphosphinyl]-L-alanine,1-methylethyl ester, 6-ester with 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile
CAS Number
1911578-83-0
Synonyms
  • Anti-virus agent 1
  • GS-5734 isopropyl ester analog
Molecular Formula
C24H29N6O8P
Formula Weight
560.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlDMSO:PBS (pH 7.2) (1:5): 0.1 mg/ml
λmax
246 nm
SMILES
CC(C)OC([C@H](C)N[P@](OC[C@@H]1[C@@H](O)[C@@H](O)[C@@](C2=CC=C3N2N=CN=C3N)(C#N)O1)(OC4=CC=CC=C4)=O)=O
InChi Code
InChI=1S/C24H29N6O8P/c1-14(2)36-23(33)15(3)29-39(34,38-16-7-5-4-6-8-16)35-11-18-20(31)21(32)24(12-25,37-18)19-10-9-17-22(26)27-13-28-30(17)19/h4-10,13-15,18,20-21,31-32H,11H2,1-3H3,(H,29,34)(H2,26,27,28)/t15-,18+,20+,21+,24-,39-/m0/s1
InChi Key
QXBLGVOITWEDBZ-QNYHHDFTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $129

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    5 mg

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    Product Description

    Remdesivir isopropyl ester analog is a derivative of the antiviral prodrug remdesivir (Item No. 30354).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Li, J., de Melo Jorge, D.M., Wang, W., et al. Differential bioactivation profiles of different GS-441524 prodrugs in cell and mouse models: ProTide prodrugs with high cell permeability and susceptibility to cathepsin a are more efficient in delivering antiviral active metabolites to the lung. J. Med. Chem. (2024).