An internal standard for the quantification of 2-nonyl-3-hydroxy-4-quinolone
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2-nonyl-3-hydroxy-4-Quinolone-d4

Item No. 9003969

Technical Information
Formal Name
3-hydroxy-2-nonyl-4(1H)-quinolinone-d4
Synonyms
  • C9-PQS-d4
Molecular Formula
C18H21D4NO2
Formula Weight
Purity
≥99% deuterated forms (d1-d4)
Formulation
A solid
DMF: 15 mg/mlDMSO: 25 mg/mlEthanol: 5 mg/ml
SMILES
O=C1C(O)=C(CCCCCCCCC)NC2=C1C([2H])=C([2H])C([2H])=C2[2H]
InChi Code
InChI=1S/C18H25NO2/c1-2-3-4-5-6-7-8-13-16-18(21)17(20)14-11-9-10-12-15(14)19-16/h9-12,21H,2-8,13H2,1H3,(H,19,20)/i9D,10D,11D,12D
InChi Key
IQZSNBAQPVKMLG-IRYCTXJYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    2-nonyl-3-hydroxy-4-Quinolone-d4 is intended for use as an internal standard for the quantification of 2-nonyl-3-hydroxy-4-quinolone (Item No. 9002699) by GC- or LC-MS. 2-nonyl-3-hydroxy-4-Quinolone is a bacterial quorum-sensing signal molecule produced by P. aeruginosa.1 It activates a biosensor for the P. aeruginosa gene pqsA, which encodes the first enzyme in the P. aeruginosa biosynthesis of the bacterial quorum-sensing signal molecule 2-heptyl-3-hydroxy-4-quinolone (Item No. 29186), in a concentration-dependent manner.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nguyen, A.T., Jones, J.W., Ruge, M.A., et alIron depletion enhances production of antimicrobials by Pseudomonas aeruginosa. J. Bacteriol. 197(14), 2265-2275 (2015).

    2. Fletcher, M.P., Diggle, S.P., Crusz, S.A., et alA dual biosensor for 2-alkyl-4-quinolone quorum-sensing signal molecules. Environ. Microbiol. 9(11), 2683-2693 (2007).