A fluorescent and reactive probe for ketones
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para-methoxy-2-amino Benzamidoxime

Item No. 9004402

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-amino-N-hydroxy-5-methoxy-benzenecarboximidamide
CAS Number
1359828-78-6
Synonyms
  • PMA
  • p-methoxy-2-amino Benzamidoxime
Molecular Formula
C8H11N3O2
Formula Weight
181.2
Purity
≥95%
Emission
515 nm
Excitation
389 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/mlDMSO: Sparingly soluble: 1-10 mg/mlMethanol: Slightly soluble: 0.1-1 mg/ml
SMILES
N=C(C1=C(N)C=CC(OC)=C1)NO
InChi Code
InChI=1S/C8H11N3O2/c1-13-5-2-3-7(9)6(4-5)8(10)11-12/h2-4,12H,9H2,1H3,(H2,10,11)
InChi Key
HGLXSWJBLALGCQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $83

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    10 mg

    $132

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    25 mg

    $269

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    50 mg

    $455

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    Product Description

    para-methoxy-2-amino-Benzamidoxime (PMA) is a fluorescent and reactive probe for ketones.1 Upon binding to ketones, PMA displays excitation/emission maxima of 389 and 515 nm, respectively. It has been used in the detection of alcohol dehydrogenases (ADHs), which convert alcohols to ketones.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mei, Z., Zhang, K., Qu, G., et al. High-throughput fluorescence assay for ketone detection and its applications in enzyme mining and protein engineering. ACS Omega 5(23), 13588-13594 (2020).