An ω-9 fatty acid
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5(Z),8(Z),11(Z)-Eicosatrienoic Acid

Item No. 90190

Technical Information
Formal Name
5Z,8Z,11Z-eicosatrienoic acid
CAS Number
20590-32-3
Synonyms
  • Mead Acid
  • FA 20:3
Molecular Formula
C20H34O2
Formula Weight
Purity
≥98%
A 10 mg/ml solution in ethanol
0.1 M Na2CO3: 1 mg/mlDMF: 100 mg/mlDMSO: 100 mg/mlEthanol: Miscible
SMILES
CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)O
InChi Code
InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h9-10,12-13,15-16H,2-8,11,14,17-19H2,1H3,(H,21,22)/b10-9-,13-12-,16-15-
InChi Key
UNSRRHDPHVZAHH-YOILPLPUSA-N
Side Chain Carbon Sum
20:3
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Eicosatrienoic acid accumulates in the tissues of animals fed diets deficient in both ω-3 and ω-6 fatty acids. It can be converted to 3-series cysteinyl-leukotrienes but cannot serve as a COX substrate.1 The kidneys from essential fatty acid deficient rats are less immunogenic when transplanted, and the metabolites of eicosatrienoic acid are believed to play a role in altering the immune status of these organs.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lefkowith, J.B. Essential fatty acid deficiency: Probing the role of arachidonate in biology. Adv. Prostaglandin Thromboxane Leukot. Res. 20, 224-231 (1990).

    2. Schreiner, G.F., Flye, W., Brunt, E., et alEssential fatty acid depletion of renal allografts and prevention of rejection. Science 240(4855), 1032-1033 (1988).

    Product Citations

    Zhang, L.J., Salekeen, R., Soto-Palma, C., et alArticle polyunsaturated lipid senolytics exploit a ferroptotic vulnerability in senescent cells. Cell Press Blue 1(1), 100004 (2026).

    Yuan, C., Sidhu, R.S., Kuklev, D.V., et alCyclooxygenase allosterism, fatty acid-mediated cross-talk between monomers of cyclooxygenase homodimers. The Journal of Biological Chemisty 284(15), 10046-10055 (2009).