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5(Z),8(Z),11(Z)-Eicosatrienoic Acid Ethanolamide

Item No. 90195

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-hydroxyethyl)-5Z,8Z,11Z-eicosatrienamide
CAS Number
169232-04-6
Synonyms
  • Mead Acid Ethanolamide
Molecular Formula
C22H39NO2
Formula Weight
349.6
Purity
≥98%
Formulation
A 5 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
1 mg/ml EtOH:PBS pH 7.2: can dilute to 1:1.6 (>38 µg/m10 mg/ml EtOH:PBS pH 7.2: can dilute to 1:1 (>5 µg/ml) (100 ?g/ml EtOH:PBS pH 7.2: can dilute to 1:1.6 (>38 µg/mlDMF: >10 mg/ml (from AEA)DMSO: >30 mg/ml (from AEA)Ethanol: >100 mg/ml (from AEA)PBS pH 7.2: <100 µg/ml (from AEA)
SMILES
CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)NCCO
InChi Code
InChI=1S/C22H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h9-10,12-13,15-16,24H,2-8,11,14,17-21H2,1H3,(H,23,25)/b10-9-,13-12-,16-15-
InChi Key
YKGQBEGMUSSPFY-YOILPLPUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 µg

    $83

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    5 mg

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    Product Description

    5(Z),8(Z),11(Z)-Eicosatrienoic acid ethanolamide is essentially identical to AEA in its agonist binding to CB1 and CB2 receptors. In L cells expressing the human CB1 receptor, the Ki value for 5(Z),8(Z),11(Z)-eicosatrienoic acid ethanolamide and AEA binding is 753 nM. In AtT-20 cells expressing the human CB2 receptor, 5(Z),8(Z),11(Z)-eicosatrienoic acid ethanolamide and AEA bind with a Ki value of 1,810 nM.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Priller, J., Briley, E.M., Mansouri, J., et al. Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors. Mol. Pharmacol. 48, 288-292 (1995).