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Dihomo-γ-Linolenoyl Ethanolamide

Item No. 90235

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-hydroxyethyl)-8Z,11Z,14Z-eicosatrienamide
CAS Number
150314-34-4
Molecular Formula
C22H39NO2
Formula Weight
349.6
Purity
≥98%
Formulation
A 25 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 30 mg/mlEthanol: 100 mg/mlEthanol:PBS (1:2): 8 mg/mlPBS (pH 7.2): <100 µg/ml
SMILES
CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)NCCO
InChi Code
InChI=1S/C22H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,24H,2-5,8,11,14-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-
InChi Key
ULQWKETUACYZLI-QNEBEIHSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $69

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    10 mg

    $127

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    50 mg

    $525

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    100 mg

    $918

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    Product Description

    Dihomo-γ-linolenoyl ethanolamide is an endocannabinoid containing dihomo-γ-linoleate in place of the arachidonate moiety of AEA. Dihomo-γ-linolenoyl ethanolamide binds to recombinant human CB1 and CB2 receptors with Ki values of 857 and 598 nM, respectively.1 Its specific role and relative importance as a cannabinergic neurotransmitter has not been elucidated.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Felder, C.C., Joyce, K.E., Briley, E.M., et al. Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. Mol. Pharmacol. 48(3), 443-450 (1995).

    2. Hanus, L., Gopher, A., Almog, S., et al. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J. Med. Chem. 36(20), 3032-3034 (1993).