A synthetic analog of palmitoyl ethanolamide
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Palmitoyl N-Isopropylamide

Item No. 91354

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-isopropyl-hexadecanamide
CAS Number
189939-61-5
Synonyms
  • PIA
Molecular Formula
C19H39NO
Formula Weight
297.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlEthanol: 20 mg/ml
SMILES
CCCCCCCCCCCCCCCC(=O)NC(C)C
InChi Code
InChI=1S/C19H39NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(21)20-18(2)3/h18H,4-17H2,1-3H3,(H,20,21)
InChi Key
TZYVUGCYYQOTQR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $53

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    10 mg

    $98

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    50 mg

    $409

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    100 mg

    $711

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    Product Description

    Palmitoyl N-isopropylamide (PIA) is a synthetic analog of palmitoyl ethanolamide which incorporates isopropyl amide in place of the native ethanolamide. PIA does not bind appreciably to either CB1 or CB2 receptors.1 PIA inhibits both the transport (re-uptake) of tritiated AEA into intact cells, as well as the subsequent hydrolysis of AEA to arachidonate and ethanolamine, with 50% inhibition of FAAH-mediated hydrolysis at 10 µM.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jonsson, K.O., Vandevoorde, S., Lambert, D.M., et al. Effects of homologues and analogues of palmitoylethanolamide upon the inactivation of the endocannabinoid anandamide. Br. J. Pharmacol. 133(8), 1263-1275 (2001).