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Oxidative stress occurs when there is an imbalance between the production of chemically reactive species such as reactive oxygen, nitrogen, and sulfur species (ROS, RNS, RSS) and antioxidant defense mechanisms. Uncontrolled oxidation can disrupt redox signaling and cause injury to cellular components like lipids, proteins, and DNA/RNA, resulting in irreparable damage and eventual cell death. Cayman offers a collection of assays for both the direct measurement of reactive species as well as markers of oxidative stress.
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