ANN ARBOR, MI, SEPTEMBER 20, 2023—Cayman Chemical, a leading supplier of bioactive lipids, has developed Cayman LipiDOT Strips™ as a research tool for the rapid identification of protein-lipid interactions. This new tool allows researchers to maximize the information gained from early protein-lipid interaction screening campaigns, giving researchers greater insight into protein-lipid interactions while being simple to perform, low cost, and easily completed in a single day.

Cayman LipiDOT Strips™ can be used to identify one or more lipids interacting with a protein of interest, assess a protein's relative lipid-binding specificity, and/or identify protein candidates for in-depth lipid-binding analysis. By identifying new lipid-protein interactions, researchers can better understand the important roles of lipids in modulating protein function and gain important insights into the biology of diseases and biological processes, which may prove useful in the pursuit of new therapeutic avenues.

Cayman LipiDOT Strips™ - PIPs Plus is the first introduction to Cayman's new product group. It includes 22 biologically relevant lipids arranged in a preconfigured panel. Cayman LipiDOT Strips™ - PIPs Plus contains several types of lipids, such as phospholipids, including a variety of phosphatidylinositol phosphate (PIP) species, lysophospholipids, and cardiolipin, as well as cholesterol and sphingolipids. These lipids interact with a variety of proteins to regulate signaling events, nutrient and energy metabolism, lipid transport, and cell adhesion, among other processes.

Custom biophysical characterization and structural biology solutions are also provided by Cayman to further characterize protein-lipid interactions.

Cayman LipiDOT Strips™ - PIPs Plus is available through Cayman online.

About Cayman Chemical
Cayman Chemical helps make research possible by supplying scientists worldwide with biochemical tools used to understand cancer, neurochemistry, oxidative injury, endocrinology, atherosclerosis, and other human health challenges. Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others for use as research reagents and qualified standards. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination. In addition, we offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques. Cayman performs generic drug development and production in both Ann Arbor, Michigan and Neratovice, Czech Republic. Learn more at www.caymanchem.com.