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Luteolin

Item № 10004161
CAS № 491-70-3
Purity ≥98%
product image
                (CAS 491-70-3)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     10 mg $19.00 0.00
     50 mg $43.00 0.00
     100 mg $76.00 0.00
     500 mg $333.00 0.00

Pricing updated 2019-04-24. Prices are subject to change without notice.

Description

Diets high in fiber contain plant lignan species that may be directly responsible for some observed health benefits of these diets.1 Luteolin is a polyphenolic flavone found in many plants including soybeans and perilla leaves.2 Luteolin is one of the most potent flavanoid inhibitors of soybean and reticulocyte 15-lipoxygenases, with an IC50 of 0.6 µM.3 Luteolin has also been found to inhibit the release of TNFα from neutrophils, and to inhibit matrix metalloproteinases.4

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Technical Information
Formal Name
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
CAS Number
491-70-3
Molecular Formula
C15H10O6
Formula Weight
286.2
Purity
≥98%
Formulation
A crystalline solid
λmax
255, 348 nm
SMILES
Oc1cc(O)c2c(=O)cc(oc2c1)c1ccc(O)c(O)c1
InChI Code
InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
InChI Key
IQPNAANSBPBGFQ-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Morton, L.W., Caccetta, R.A.A., Puddey, I.B., et al. Chemistry and biological effects of dietary phenolic compounds: Relevance to cardiovascular disease Clinical and Experimental Pharmacology and Physiology 27, 152-159 (2000).

2. Ueda, H., Yamazaki, C., and Yamazaki, M. Luteolin as an anti-inflammatory and anti-allergic constituent of Perilla frutescens Biological and Pharmaceutical Bullentin 25(9), 1197-1202 (2002).

3. Sadik, C.D., Sies, H., and Schewe, T. Inhibition of 15-lipoxygenases by flavonoids: Structure-activity relations and mode of action Biochemical Pharmacology 65, 773-781 (2003).

4. Sartor, L., Pezzato, E., Dell'Aica, I., et al. Inhibition of matrix-proteases by polyphenols: Chemical insights for anti-inflammatory and anti-invasion drug design Biochemical Pharmacology 64, 229-237 (2002).

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