Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Visit our FAQ
Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888
Product Categories
Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.
CAY10444 is a sphingosine-1-phosphate receptor 3 (S1P3) antagonist.1 It inhibits S1P-induced calcium mobilization in CHO cells expressing human S1P3 (IC50 = 11.6 µM). CAY10444 (5 µM) inhibits S1P-induced growth and migration of MH7A rheumatoid fibroblast-like synoviocyte cells.2 It inhibits the localization and release of IL-1β and prostaglandin E2 (PGE2; Item No. 14010) in MH7A cells when used at a concentration of 5 µM. CAY10444 (17.4 µM) also inhibits Na+/K+-ATPase activity in HepG2 cells.3
WARNING This product is not for human or veterinary use.
1. .
2. .
3. .
.
.
.