A synthetic progestin
Related Products
Labeled Version(s)
25231Levonorgestrel-d6
Metabolite(s)
278545α-dihydro Levonorgestrel
Pro-drug Form(s)
16547Norgestimate
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Levonorgestrel

Item No. 10006318

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
13-ethyl-17α-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one
CAS Number
797-63-7
Molecular Formula
C21H28O2
Formula Weight
312.5
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 5 mg/mlDMSO:PBS (pH 7.2)(1:2): .3 mg/mlEthanol: .2 mg/ml
λmax
240 nm
SMILES
O[C@@]1(C#C)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4([H])[C@@]3([H])CC[C@@]21CC)=O
InChi Code
InChI=1S/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1
InChi Key
WWYNJERNGUHSAO-XUDSTZEESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Levonorgestrel is a synthetic progestin and the biologically active component of norgestrel (Item No. 10006319).1 In vivo, levonorgestrel (60 μg/day) suppresses estrus and pregnancy in female cats.2 Post-coital insertion of subdermal levonorgestrel (5 mg pellet) implants prevents uterine implantation of embryos in mice.3 Formulations containing levonorgestrel have been used as contraceptives.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jones, R.C., Singer, A.C., and Edgren, R.A. The biological activities of norgestrel and its enantiomers. Int. J. Fertil. 24(1), 39-43 (1979).

    2. Baldwin, C.J., Peter, A.T., Bosu, W.T., et al. The contraceptive effects of levonorgestrel in the domestic cat. Lab. Anim. Sci. 44(3), 261-269 (1994).

    3. Shirley, B., Bundren, J.C., and McKinney, S. Levonorgestrel as a postcoital contraceptive. Contraception 52(2), 277-281 (1995).