A product of lipid biosynthesis
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1-Palmitoyl-2-Linoleoyl-sn-glycero-3-PE

Item No. 10007072

Technical Information
Formal Name
9Z,12Z-octadecadienoic acid, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester
CAS Number
26662-95-3
Synonyms
  • 1-Palmitoyl-2-Linoleoyl PE
  • PLPE
  • (1-Palmitoyl, 2-Linoleoyl)-Phosphatidylethanolamine
  • (1-Palmitoyl, 2-Linoleoyl)-Phosphoethanolamine
Molecular Formula
C39H74NO8P
Formula Weight
Purity
≥95% (9:1 mixture of 1':2' acyl chain positional isomers)
A crystalline solid
Chloroform: 50 mg/mlEthanol: 1 mg/mlMethanol: 5 mg/ml
SMILES
O=C(CCCCCCCCCCCCCCC)OC[C@@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COP([O-])(OCC[NH3+])=O
InChi Code
InChI=1S/C39H74NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h11,13,17-18,37H,3-10,12,14-16,19-36,40H2,1-2H3,(H,43,44)/b13-11-,18-17-/t37-/m1/s1
InChi Key
HBZNVZIRJWODIB-NHCUFCNUSA-N
Side Chain Carbon Sum
34:2
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE (PLPE) is one of the many phosphatidylethanolamines that may be present in cellular membranes. It has been used in studies involving the biosynthesis of anandamide via the phospholipase A2 (PLA2) and lysoPLD pathways.1 PLPE can also be used as a specific substrate to assess the activity of sPLA2-IIA in the presence of other phospholipids.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sun, Y.X., Tsubio, K., Okamoto, Y., et alBiosynthesis of anandamide and N-palmitoylethanolamide by sequential actions of phospholipase A2 and lysophosphase D. J. Biochem. 380(Pt 3), 749-755 (2004).

    2. Yang, H.C., Mosior, M., Johnson, C.A., et alGroup-specific assays that distinguish between the four major types of mammalian phospholipase A2. Anal. Biochem. 269(2), 278-288 (1999).