Sphingolipid pathway intermediate
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Labeled Version(s)
27145Sphinganine-d7 (d18:0)
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Sphinganine (d18:0)

Item No. 10007945

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2S-amino-1,3R-octadecanediol
CAS Number
764-22-7
Synonyms
  • Dihydrosphingosine
  • D-erythro-Dihydrosphingosine
  • Dihydro-D-erythro Sphingosine
  • Sphinganine
  • D-erythro-Sphinganine
Molecular Formula
C18H39NO2
Formula Weight
301.5
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 2 mg/mlEthanol: Miscible
SMILES
OC[C@H](N)[C@H](O)CCCCCCCCCCCCCCC
InChi Code
InChI=1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
InChi Key
OTKJDMGTUTTYMP-ZWKOTPCHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Sphinganine (d18:0) is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins,1,2 as well as in some cancers.3 Sphinganine can block protein kinase C activation in some cases but not others.4,5 Sphinganine-1-phosphate can emulate sphingosine-1-phosphate in cell signaling or have opposite intracellular effects.6,7,8

    WARNING This product is not for human or veterinary use.