An esterified form of α-linolenic acid
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α-Linolenic Acid ethyl ester

Item No. 10008199

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9Z,12Z,15Z-octadecatrienoic acid, ethyl ester
CAS Number
1191-41-9
Synonyms
  • ALAEE
  • Ethyl α-Linolenate
  • Ethyl Linolenate
  • LAEE
  • Linolenic Acid ethyl ester
  • SFE 20:3
Molecular Formula
C20H34O2
Formula Weight
306.5
Purity
≥98%
Formulation (Request formulation change)
A 500 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: >100 mg/mlDMSO: >100 mg/mlEthanol: >100 mg/ml
SMILES
CC/C=C\C/C=C\C/C=C\CCCCCCCC(OCC)=O
InChi Code
InChI=1S/C20H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22-4-2/h5-6,8-9,11-12H,3-4,7,10,13-19H2,1-2H3/b6-5-,9-8-,12-11-
InChi Key
JYYFMIOPGOFNPK-AGRJPVHOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    50 mg

    $32

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    100 mg

    $52

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    500 mg

    $91

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    1 g

    $149

    Add
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    Product Description

    α-Linolenic acid ethyl ester is an esterified form of α-linolenic acid (Item Nos. 90210 | 21910). It increases cyclin E levels and the activity of Cdk2/cyclin E, ERK, and JNK in hepatic stellate cells when used at a concentration of 50 μM.1 α-Linolenic acid ethyl ester (25 μg/ml) inhibits the growth of S. mutans, C. albicans, and P. gingivalis by 98, 72, and 92%, respectively, in vitro.2 It has been found in biodiesel produced from castor oil using ethanol.3 α-Linolenic acid ethyl ester has been used as a substrate in lipid peroxidation assays for antioxidant activity.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, J., Hu, W., Baldassare, J.J., et al. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life Sci. 73(9), 1083-1096 (2003).

    2. Huang, C.B., and Ebersole, J.L. A novel bioactivity of omega-3 polyunsaturated fatty acids and their ester derivatives. Mol. Oral Microbiol. 25(1), 75-80 (2010).

    3. Conceição, M.M., Fernandes, V.J., Jr., Bezerra, A.F., et al. Dynamic kinetic calculation of castor oil biodiesel. J. Therm. Anal. Calorim. 87(3), 865-869 (2007).

    4. Miyake, T., and Shibamoto, T. Antioxidative activities of natural compounds found in plants. J. Agric. Food Chem. 45(5), 1819-1822 (1997).

    Product Citations

    Huang, C.B., and Ebersole, J.L. A novel bioactivity of omega-3 polyunsaturated fatty acids and their ester derivatives. Mol. Oral Microbiol. 25(1), 75-80 (2010).