For immunochemical detection of PCSK9
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PCSK9 (mouse) Polyclonal Antibody

Item No. 10008811

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • NARC-1
  • Proprotein Convertase Subtilisin Kexin 9
Immunogen
Synthetic peptide from an internal region of mouse PCSK9
Formulation (Request formulation change)
500 µl of peptide affinity-purified polyclonal antibody
Storage Buffer
PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide
Host
Rabbit
Applications
IF and WB
Species Reactivity
(+) Human(+) Mouse(+) Rat
UniProt Accession №
Q80W65
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 ea (500 µl)

    $347

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    Cayman Chemical
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    Product Description

    PCSK9 mRNA is detected in various tissues such as liver, kidney, lung, spleen, jejunum, ileum, colon, and muscle with the highest expression in the liver.1 Human PCSK9 precursor is 692 amino acid in length with an estimated molecular weight of 74 kDa. This proprotein is self-cleaved to form a mature protein at around 63 kDa in the Golgi.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Seidah, N.G., Benjannet, S., Wickham, L., et al. The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation. Proc. Natl. Acad. Sci. USA 100(3), 928-933 (2003).

    2. Maxwell, K.N., and Breslow, J.L. Proprotein convertase subtilisin kexin 9: The third locus implicated in autosomal dominant hypercholesterolemia. Curr. Opin. Lipidol. 16(2), 167-172 (2005).