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ERK/MAPK (Phospho-Thr202/Tyr204) Polyclonal Antibody

Item № 10009179
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 ea $345.00 0.00

Pricing updated 2019-05-23. Prices are subject to change without notice.

Description

Extracellular-signal regulated kinase/mitogen-activated protein kinase (ERK/MAPK) is an integral component of cellular signaling during mitogenesis and differentiation of mitotic cells and also is thought to play a key role in learning and memory.1,2,3,4 The activity of this kinase is regulated by dual phosphorylation at Thr202 and Tyr204.3

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Technical Information
Immunogen
phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr202 and phospho-Tyr204 of rat ERK/MAPK
Formulation
Affinity-purified IgG
Host
rabbit
Applications
WB
Species Reactivity
  • (+) Human ERK/MAPK
  • (+) Rat ERK/MAPK
Origin
  • Animal/Rabbit

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Johnson, G.L., and Lapadat, R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases Science 298, 1911-1912 (2002).

2. Adams, J.P., and Sweatt, J.D. Molecular psychology: Roles for the ERK MAP kinase cascade in memory Annu. Rev. Pharmacol. Toxicol. 42, 135-163 (2002).

3. Ahn, N.G. The MAP kinase cascade. Discovery of a new signal transduction pathway Mol. Cell Biochem. 127-128, 201-209 (1993).

4. Tanoue, T.J., and Nishida, E. Molecular recognitions in the MAP kinase cascades Cellular Signalling 15, 455-462 (2003).

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