For immunochemical detection of ERK/MAPK
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ERK/MAPK (Phospho-Thr202/Tyr204) Polyclonal Antibody

Item No. 10009179

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Immunogen
phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr202 and phospho-Tyr204 of rat ERK/MAPK
Formulation (Request formulation change)
Affinity-purified IgG
Host
Rabbit
Applications
WB
Species Reactivity
(+) Human ERK/MAPK(+) Rat ERK/MAPK
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Extracellular-signal regulated kinase/mitogen-activated protein kinase (ERK/MAPK) is an integral component of cellular signaling during mitogenesis and differentiation of mitotic cells and also is thought to play a key role in learning and memory.1,2,3,4 The activity of this kinase is regulated by dual phosphorylation at Thr202 and Tyr204.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Johnson, G.L., and Lapadat, R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298(5600), 1911-1912 (2002).

    2. Adams, J.P., and Sweatt, J.D. Molecular psychology: Roles for the ERK MAP kinase cascade in memory. Annu. Rev. Pharmacol. Toxicol. 42, 135-163 (2002).

    3. Ahn, N.G. The MAP kinase cascade. Discovery of a new signal transduction pathway. Mol. Cell Biochem. 127-128, 201-209 (1993).

    4. Tanoue, T.J., and Nishida, E. Molecular recognitions in the MAP kinase cascades. Cell. Signal. 15, 455-462 (2003).