An internal standard for the quantification of 2,3-dinor Thromboxane B2
Related Products
Unlabeled Version(s)
190502,3-dinor Thromboxane B2
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

2,3-dinor Thromboxane B2-d9

Item No. 10009584

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(Z)-5-((2R,3S,4S)-4,6-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl-5,5,6,6,7,7,8,8,8-d9)tetrahydro-2H-pyran-3-yl)pent-3-enoic acid
Synonyms
  • 2,3-dinor TXB2-d9
Molecular Formula
C18H21D9O6
Formula Weight
351.5
Purity
≥99% deuterated forms (d1-d9)
Formulation
A 100 µg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: >50 mg/mLDMSO: >25 mg/mLEthanol: >100 mg/mLPBS (pH 7.2): >100 mg/mL
SMILES
O[C@@H]1[C@H](C/C=C\CC(O)=O)[C@@H](/C=C/[C@@H](O)CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])OC(O)C1
InChi Code
InChI=1S/C18H30O6/c1-2-3-4-7-13(19)10-11-16-14(8-5-6-9-17(21)22)15(20)12-18(23)24-16/h5-6,10-11,13-16,18-20,23H,2-4,7-9,12H2,1H3,(H,21,22)/b6-5-,11-10+/t13-,14-,15-,16+,18?/m0/s1/i1D3,2D2,3D2,4D2
InChi Key
RJHNVFKNIJQTQF-NADUYOJDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 µg

    $201

    Add

    50 µg

    $378

    Add

    100 µg

    $712

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    2,3-dinor Thromboxane B2-d9 (2,3-dinor TXB2-d9) is intended for use as an internal standard for the quantification of 2,3-dinor TXB2 (Item No. 19050) by GC- or LC-MS. TXB2 is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.1 2,3-dinor TXB2 is an abundant urinary metabolite of TXB2 and can be used as a marker for in vivo TXA2 synthesis.1,2,3 In healthy male volunteers, the median excretion of 2,3-dinor TXB2 is 10.3 ng/hour (138 pg/mg creatine).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ciabattoni, G., Pugliese, F., Davi, G., et al. Fractional conversion of thromboxane B2 to urinary 11-dehydrothromboxane B2 in man. Biochim. Biophys. Acta 992(1), 66-70 (1989).

    2. Lawson, J.A., Brash, A.R., Doran, J., et al. Measurement of urinary 2,3-dinor-thromboxane B2 and thromboxane B2 using bonded-phase phenylboronic acid columns and capillary gas chromatography-negative-ion chemical ionization mass spectrometry. Anal. Biochem. 150, 463-470 (1985).

    3. Lawson, J.A., Patrono, C., Ciabattoni, G., et al. Long-lived enzymatic metabolites of thromboxane B2 in the human circulation. Anal. Biochem. 155(1), 198-205 (1986).

    Product Citations

    Yang, J., Yamashita-Kanemaru, Y., Morris, B.I., et al. Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity. Nature (2025).