A synthetic, short-chain lecithin compound
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1,2-Didecanoyl-sn-glycero-3-PC

Item No. 10009879

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,2-bis(O-decanoyl)-sn-glyceryl-3-phosphorylcholine
CAS Number
3436-44-0
Synonyms
  • 1,2-Didecanoyl Phosphatidylcholine
  • Didecanoyl Lecithin
  • 1,2-Didecanoyl PC
  • 1,2-DPC
Molecular Formula
C28H56NO8P
Formula Weight
565.7
Purity
≥98%
Formulation (Request formulation change)
A 25 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2)(1:1): 0.5 mg/ml
SMILES
CCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N](C)(C)C)OC(=O)CCCCCCCCC
InChi Code
InChI=1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3/t26-/m1/s1
InChi Key
MLKLDGSYMHFAOC-AREMUKBSSA-N
Side Chain Carbon Sum
20:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $20

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    10 mg

    $35

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    25 mg

    $75

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    50 mg

    $129

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    Cayman Chemical
    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
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    Product Description

    Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Didecanoyl PC (DPC) is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin. Thus, the bioavailability of intranasally applied human growth hormone is enhanced when coadministered with the absorption enhancer DPC.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Agerholm, C., Bastholm, L., Johansen, P.B., et al. Epithelial transport and bioavailability of intranasally administered human growth hormone formulated with the absorption enhancers didecanoyl-L-α-phosphatidylcholine and α-cyclodextrin in rabbits. J. Pharm. Sci. 83(12), 1706-1711 (1994).