An ether analog of lysophosphatidic acid
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1-Palmityl-2-hydroxy-sn-glycero-3-PA

Item No. 10010188

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(hexadecyloxy)-1-(dihydrogen phosphate)-1,2R-propanediol
CAS Number
52603-03-9
Synonyms
  • 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate
  • 1-Hexadecyl LPA
  • 1-Hexadecyl Lysophosphatidic Acid
  • LPA O-16:0
  • O-16:0 LPA
  • PA(O-16:0/0:0)
  • 1-Palmityl LPA
  • 1-Palmityl Lysophosphatidic Acid
Molecular Formula
C19H41O6P
Formula Weight
396.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 20 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2)(1:1): 0.5 mg/ml
SMILES
CCCCCCCCCCCCCCCCOC[C@@H](O)COP(O)(O)=O
InChi Code
InChI=1S/C19H41O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-24-17-19(20)18-25-26(21,22)23/h19-20H,2-18H2,1H3,(H2,21,22,23)/t19-/m1/s1
InChi Key
XLVRFPVHQPHXAA-LJQANCHMSA-N
Side Chain Carbon Sum
16:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    1-Palmityl-2-hydroxy-sn-glycero-3-PA is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.1 LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tsukahara, T., Tsukahara, R., Yasuda, S., et al. Different residues mediate recognition of 1-O-oleyl-lysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor γ. The Journal of Biological Chemisty 281(6), 3398-3407 (2006).

    2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions. Trends Cell Biol. 4(6), 213-219 (1994).

    3. Chun, J., Goetzl, E.J., Hla, T., et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol. Rev. 54(2), 265-269 (2002).