An ether analog of LPA
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Alternative(s)
100101881-Palmityl-2-hydroxy-sn-glycero-3-PA
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1-Palmityl-2-hydroxy-sn-glycero-3-PA (sodium salt)

Item No. 10010292

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(hexadecyloxy)-1-(dihydrogen phosphate)-1,2-propanediol, monosodium salt
Synonyms
  • 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate
  • 1-Hexadecyl LPA
  • 1-Hexadecyl Lysophosphatidic Acid
  • LPA O-16:0
  • O-16:0 LPA
  • PA(O-16:0/0:0)
  • 1-Palmityl LPA
  • 1-Palmityl Lysophosphatidic Acid
Molecular Formula
C19H40O6P • Na
Formula Weight
418.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform:Methanol:Acetic Acid (95:5:5): 1 mg/ml
SMILES
CCCCCCCCCCCCCCCCOC[C@@H](O)COP([O-])(O)=O.[Na+]
InChi Code
InChI=1S/C19H41O6P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-24-17-19(20)18-25-26(21,22)23;/h19-20H,2-18H2,1H3,(H2,21,22,23);/q;+1/p-1/t19-;/m1./s1
InChi Key
KTKBITOTGQCJRQ-FSRHSHDFSA-M
Side Chain Carbon Sum
16:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

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    Product Description

    1-Palmityl-2-hydroxy-sn-glycero-3-PA (sodium salt) is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.1 LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tsukahara, T., Tsukahara, R., Yasuda, S., et al. Different residues mediate recognition of 1-O-oleyl-lysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor γ. The Journal of Biological Chemisty 281(6), 3398-3407 (2006).

    2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions. Trends Cell Biol. 4(6), 213-219 (1994).

    3. Chun, J., Goetzl, E.J., Hla, T., et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol. Rev. 54(2), 265-269 (2002).