A prodrug form of PGA1
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Active Metabolite(s)
10010Prostaglandin A1
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Prostaglandin A1 ethyl ester

Item No. 10020

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
15S-hydroxy-9-oxo-prosta-10,13E-dien-1-oic acid, ethyl ester
CAS Number
93464-24-5
Synonyms
  • PGA1 ethyl ester
Molecular Formula
C22H36O4
Formula Weight
364.5
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 0.25 mg/ml
λmax
218 nm
SMILES
O=C1[C@H](CCCCCCC(OCC)=O)[C@@H](/C=C/[C@@H](O)CCCCC)C=C1
InChi Code
InChI=1S/C22H36O4/c1-3-5-8-11-19(23)16-14-18-15-17-21(24)20(18)12-9-6-7-10-13-22(25)26-4-2/h14-20,23H,3-13H2,1-2H3/b16-14+/t18-,19-,20+/m0/s1
InChi Key
STQVEMJKKQYNQQ-LTGPBHORSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    10 mg

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    Product Description

    Prostaglandin A1 (PGA1) ethyl ester is a prodrug form of PGA1 with enhanced lipid solubility. Prostaglandins of the A-series are natural products of gorgonian soft coral. PGA1 has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients.1 There are no published reports on the biological activity of PGA1 ethyl ester at this time.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Krakoff, L.R., Vlachakis, N., Mendlowitz, M., et al. Differential effect of prostaglandin A1 in hypertensive patients with low, normal and high renin. Clin. Sci. Mol. Med. Suppl. 2, 311s-313s (1975).