A nitrated fatty acid and PPARγ agonist
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10-Nitrolinoleate

Item No. 10037

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
10-nitro-9E,12Z-octadecadienoic acid
CAS Number
774603-04-2
Synonyms
  • 10-LNO2
  • 10-NO2-LA
  • 10-nitro-9,12-Octadecadienoic Acid
Molecular Formula
C18H31NO4
Formula Weight
325.4
Purity
≥95%
Formulation
A 1 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/mlEthanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
λmax
249 nm
SMILES
CCCCC/C=C\C/C([N+]([O-])=O)=C\CCCCCCCC(O)=O
InChi Code
InChI=1S/C18H31NO4/c1-2-3-4-5-8-11-14-17(19(22)23)15-12-9-6-7-10-13-16-18(20)21/h8,11,15H,2-7,9-10,12-14,16H2,1H3,(H,20,21)/b11-8-,17-15+
InChi Key
LELVHAQTWXTCLY-XYWKCAQWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    10-Nitrolinoleate is a nitrated fatty acid and a peroxisome proliferator-activated receptor γ (PPARγ) agonist.1 It is formed from linoleic acid (Item Nos. 90150 | 90150.1 | 21909) upon exposure to acidified nitrite.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Dunny, E., and Evans, P. Stereocontrolled synthesis of the PPAR-γ agonist 10-nitrolinoleic acid. The Journal of Organic Chemistry 75(15), 5334-5336 (2010).

    2. Woodcock, S.R., Salvatore, S.R., Bonacci, G., et al. Biomimetic nitration of conjugated linoleic acid: Formation and characterization of naturally occurring conjugated nitrodienes. The Journal of Organic Chemistry 79(1), 25-33 (2014).