A nitrated fatty acid
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Isomer(s)
1003710-Nitrolinoleate
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9(E),11(E)-9-nitro Conjugated Linoleic Acid

Item No. 30160

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(9E,11E)-9-nitro-9,11-octadecadienoic acid
CAS Number
1417651-32-1
Synonyms
  • 9E,11E-9-nitro CLA
Molecular Formula
C18H31NO4
Formula Weight
325.4
Purity
≥95%
Formulation (Request formulation change)
A 500 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
0.1M Na2CO3: 1 mg/mlDMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/ml
SMILES
CCCCCC/C=C/C=C(CCCCCCCC(O)=O)/[N+]([O-])=O
InChi Code
InChI=1S/C18H31NO4/c1-2-3-4-5-6-8-11-14-17(19(22)23)15-12-9-7-10-13-16-18(20)21/h8,11,14H,2-7,9-10,12-13,15-16H2,1H3,(H,20,21)/b11-8+,17-14+
InChi Key
URRNFVDDJZKQGD-LDRANXPESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 µg

    $43

    Add

    100 µg

    $82

    Add

    250 µg

    $194

    Add
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    Product Description

    9(E),11(E)-9-nitro Conjugated linoleic acid (9E,11E-9-nitro CLA) is a nitrated fatty acid. It is formed from 9Z,11E-CLA (Item No. 90140) upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1 It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME (Item No. 80210).2 9E,11E-9-nitro CLA has been found in human plasma.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Woodcock, S.R., Salvatore, S.R., Bonacci, G., et al. Biomimetic nitration of conjugated linoleic acid: Formation and characterization of naturally occurring conjugated nitrodienes. The Journal of Organic Chemistry 79(1), 25-33 (2014).

    2. Bonacci, G., Baker, P.R.S., Salvatore, S.R., et al. Conjugated linoleic acid is a preferential substrate for fatty acid nitration. The Journal of Biological Chemisty 287(53), 44071-44082 (2012).