The 15(R) stereoisomer of PGA1
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Isomer(s)
10010Prostaglandin A1
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15-epi Prostaglandin A1

Item No. 10070

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
15R-hydroxy-9-oxo-prosta-10,13R-dien-1-oic acid
CAS Number
20897-92-1
Synonyms
  • 15-epi PGA1
Molecular Formula
C20H32O4
Formula Weight
336.5
Purity
≥98%
Formulation (Request formulation change)
A 1 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: >50 mg/mlDMSO: >75 mg/mlEthanol: >100 mg/mlPBS (pH 7.2): >2.4 mg/ml
λmax
217 nm
SMILES
CCCCC[C@@H](O)/C=C/[C@H]([C@H]1CCCCCCC(O)=O)C=CC1=O
InChi Code
InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/b14-12+/t16-,17+,18+/m0/s1
InChi Key
BGKHCLZFGPIKKU-AHUSATQRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    100 µg

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    Product Description

    15-epi Prostaglandin A1 (15-epi PGA1) is the 15(R) stereoisomer of PGA1. Prostaglandins of the A-series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive patients.1 There are no published reports on the biological activity of 15-epi PGA1 at this time.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Krakoff, L.R., Vlachakis, N., Mendlowitz, M., et al. Differential effect of prostaglandin A1 in hypertensive patients with low, normal and high renin. Clin. Sci. Mol. Med. Suppl. 2, 311s-313s (1975).