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JWH 210

Item No. 10644

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4-ethyl-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone
CAS Number
824959-81-1
Molecular Formula
C26H27NO
Formula Weight
369.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 20 mg/mlEthanol: 0.5 mg/ml
λmax
222, 247, 314 nm
SMILES
CCCCCN1C=C(C(C2=C(C=CC=C3)C3=C(CC)C=C2)=O)C4=C1C=CC=C4
InChi Code
InChI=1S/C26H27NO/c1-3-5-10-17-27-18-24(22-13-8-9-14-25(22)27)26(28)23-16-15-19(4-2)20-11-6-7-12-21(20)23/h6-9,11-16,18H,3-5,10,17H2,1-2H3
InChi Key
LACIUQLUNACUKC-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    JWH 210 (Item No. 10644) is a potent cannabimimetic alkylindole, binding the central cannabinoid and peripheral cannabinoid receptors with Ki values of 0.46 and 0.69 nM, respectively.1 The effects of JWH 210 in whole cells or organisms have not been evaluated. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. Bioorg. Med. Chem. 13(1), 89-112 (2005).

    Product Citations

    Cho, B., Cho, H.S., Kim, J., et al. Simultaneous determination of synthetic cannabinoids and their metabolites in human hair using LC-MS/MS and application to human hair. Forensic Sci. Int. 306, 110058 (2020).

    Marino, M.A., Voyer, B., Cody, R.B., et al. Rapid identification of synthetic cannabinoids in herbal incenses with DART-MS and NMR. J. Forensic Sci. 61(S1), S82-S91 (2016).

    Ciolino, L.A. Quantitation of synthetic cannabinoids in plant materials using high performance liquid chromatography with UV detection (validated method). J. Forensic Sci. 60(5), 1171-1181 (2015).