For immunochemical analysis of Nampt
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Nampt Monoclonal Antibody (Clone OMNI 379)

Item No. 10813

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Nicotinamide Phosphoribosyltransferase
  • PBEF1
  • Pre-B Cell Colony Enhancing Factor 1
  • Visfatin
Immunogen
recombinant human Nampt
Clone Designation
OMNI 379
Formulation (Request formulation change)
A 1 mg/ml solution in PBS, pH 7.4
Host
Mouse
Isotype
IgG2aκ
Applications
ELISA, FC, ICC, IHC, IP, and WB
Species Reactivity
(+) Human Nampt(+) Mouse Nampt(+) Rat Nampt
Origin
Animal/Mouse
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    50 µg

    $250

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    100 µg

    $373

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    Cayman Chemical
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    Product Description

    Nampt is a 52 kDa adipokine secreted by adipose tissue that is involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates the insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

    WARNING This product is not for human or veterinary use.