An Analytical Reference Material
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  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Methylone (hydrochloride)

Item No. 10986

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • M1
  • bk-MDMA
  • β-keto Methylenedioxy Methamphetamine
  • 3,4-Methylenedioxy-N-methylcathinone
Technical Information
Formal Name
1-(1,3-benzodioxol-5-yl)-2-(methylamino)-1-propanone, monohydrochloride
CAS Number
186028-80-8
Molecular Formula
C11H13NO3 • HCl
Formula Weight
243.7
Purity
≥98%
Formulation
A neat solid
SMILES
CC(NC)C(C1=CC(OCO2)=C2C=C1)=O.Cl
InChi Code
InChI=1S/C11H13NO3.ClH/c1-7(12-2)11(13)8-3-4-9-10(5-8)15-6-14-9;/h3-5,7,12H,6H2,1-2H3;1H
InChi Key
GASYWEXOTOXXLK-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Methylone (hydrochloride) (Item No. 10986) is an analytical reference material that is categorized as a cathinone. Methylone blocks reuptake of dopamine, 5-HT, and norepinephrine in rat synaptosomes (IC50s = 2.9, 2.3, and 0.74 µM, respectively).1 It also induces release of the same neurotransmitters from synaptosomes (EC50s = 0.38, 0.22, and 0.093 µM, respectively). It has been detected in products marketed as bath salts, plant food, and tablets.2,3 Methylone is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. Eur. J. Pharmacol. 559(2-3), 132-137 (2007).

    2. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan. Leg. Med. (Tokyo) 13(3), 109-115 (2011).

    3. Bossong, M.G., Van Dijk, J.P., and Niesink, R.J. Methylone and mCPP, two new drugs of abuse? Addict. Biol. 10(4), 321-323 (2005).

    Product Citations

    Glatfelter, G.C., Walther, D., Evans-Brown, M., et al. Eutylone and Its structural isomers interact with monoamine transporters and induce locomotor stimulation. ACS Chem. Neurosci. (2021).

    Lee, H.Z.S., Koh, H.B., Tan, S., et al. Identification of closely related new psychoactive substances (NPS) using solid deposition gas-chromatography infra-red detection (GC-IRD) spectroscopy. Forensic Sci. Int. 299, 21-33 (2019).