For screening a variety of epigenetic compounds
Features
  • Contains 229 small molecules
  • Includes compounds that modulate the activity of methyltransferases, demethylases, HATs, HDACs, and acetylated lysine reader proteins
  • Certain customizations available. Use the “Bulk & Custom” form to request.
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

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Epigenetics Screening Library (96-Well)

Item No. 11076

Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    The Epigenetics Screening Library contains 229 small molecules that are known to modulate the activity of a variety of epigenetic ‘writers and erasers’ and ‘reader’ proteins in a 96-well Matrix tube rack format as 10 mM stocks in DMSO. It may include compounds that modulate the activity of methyltransferases, demethylases, histone acetyltransferases, histone deacetylases, and acetylated histone binding proteins. Stability data is not available for individual compounds as supplied in the screening library. Panels are routinely re-evaluated to include new catalog introductions as the research evolves.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Coetzee, N., von Grüning, H., Opperman, D., et alEpigenetic inhibitors target multiple stages of Plasmodium falciparum parasites. Sci. Rep. 10(1), (2020).

    Giardina, C., Nakanishi, M., Khan, A., et alRegulation of VDR expression in Apc-mutant mice, human colon cancers and adenomas. Cancer Prev. Res. (Phila.) 8(5), 387-399 (2015).