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Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.
ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICESPatulin is a mycotoxin originally isolated from P. griseofulvum.1 It is lethal to rodents (LD50 = 29-55 mg/kg) and poultry (LD50 = 170 mg/kg), as well as induces convulsions, dyspnea, pulmonary edema and ulceration, and gastrointestinal distension in rats, mice, chickens, and hamsters. Patulin is embryotoxic in chick eggs when used at concentrations ranging from 2.35 to 68.7 µg/egg and induces hypoplasia of the mesencephalon and telencephalon, hyperplasia of the mandibular process, and growth retardation in rat embryos. It has been found in Penicillium-infected apple crops.
WARNING This product is not for human or veterinary use.
1. Biosynthesis and toxicological effects of patulin. Toxins 2(4), 613-631 (2010).