A mycotoxin
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Labeled Version(s)
31301Patulin-13C7
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Patulin

Item No. 11346

Technical Information
Formal Name
4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
CAS Number
149-29-1
Synonyms
  • Clairformin
  • Expansin
  • Mycoin C
  • NSC 8120
  • NSC 32951
  • Penicidin
  • Terinin
Molecular Formula
C7H6O4
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMF: 20 mg/mlDMSO: 10 mg/mlEthanol: 13 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
275 nm
SMILES
O=C1OC2=CCOC(O)C2=C1
InChi Code
InChI=1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2
InChi Key
ZRWPUFFVAOMMNM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Patulin is a mycotoxin originally isolated from P. griseofulvum.1 It is lethal to rodents (LD50 = 29-55 mg/kg) and poultry (LD50 = 170 mg/kg), as well as induces convulsions, dyspnea, pulmonary edema and ulceration, and gastrointestinal distension in rats, mice, chickens, and hamsters. Patulin is embryotoxic in chick eggs when used at concentrations ranging from 2.35 to 68.7 µg/egg and induces hypoplasia of the mesencephalon and telencephalon, hyperplasia of the mandibular process, and growth retardation in rat embryos. It has been found in Penicillium-infected apple crops.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Puel, O., Galtier, P., and Oswald, I.P. Biosynthesis and toxicological effects of patulin. Toxins 2(4), 613-631 (2010).