A trichothecene mycotoxin
Related Products
Labeled Version(s)
31287diacetoxy Scirpenol-13C19
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

diacetoxy Scirpenol

Item No. 11427

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3α,4β)-12,13-epoxy-trichothec-9-ene-3,4,15-triol, 4,15-diacetate
CAS Number
2270-40-8
Synonyms
  • Anguidin
  • DAS
  • NSC 141537
  • NSC 177378
  • Scirpenetriol 4,15-diacetate
Molecular Formula
C19H26O7
Formula Weight
366.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:4): 0.2 mg/mlDMSO: 30 mg/mlEthanol: 20 mg/ml
SMILES
CC1=C[C@]2([H])[C@]([C@]([C@H](OC(C)=O)[C@H]3O)(C)[C@@]4(OC4)[C@]3([H])O2)(COC(C)=O)CC1
InChi Code
InChI=1S/C19H26O7/c1-10-5-6-18(8-23-11(2)20)13(7-10)26-16-14(22)15(25-12(3)21)17(18,4)19(16)9-24-19/h7,13-16,22H,5-6,8-9H2,1-4H3/t13-,14-,15-,16-,17-,18-,19+/m1/s1
InChi Key
AUGQEEXBDZWUJY-NMAPUUFXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $88

    Add

    5 mg

    $351

    Add

    10 mg

    $657

    Add
    Cayman Chemical
    Visit Our Environmental Toxicology Resource Center

    Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.

    ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICES
    Product Description

    diacetoxy Scirpenol is a trichothecene mycotoxin originally isolated from F. equiseti.1 It is toxic to pigs (LD50 = 0.38 mg/kg, i.v.) and lethal to brine shrimp (LC50 = 0.39 µg/ml).2,3 diacetoxy Scirpenol (1 µg/ml) suppresses phagocytosis by, and superoxide production in, isolated mouse macrophages in an S. cerevisiae model of phagocytosis.4 It is toxic to barley, wheat, and sorghum seedlings (LD50s = 1.26, 3.98, and 10 mg/L, respectively).5 It has been found as a contaminant in grasses intended to be used as animal feed.6

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Dawkins, A.W., Grove, J.F., and Tidd, B.K. Diacetoxyscirpenol and some related compounds. Chem. Commun. (Lond.) 2, 27-28 (1965).

    2. Weaver, G.A., Kurtz, H.J., Mirocha, C.J., et al. Acute toxicity of the mycotoxin diacetoxyscirpenol in swine. Can. Vet. J. 19(10), 267-271 (1978).

    3. Perkowski, J., Foremska, E., and Latus-Ziętkiewicz, D. The yields of diacetoxyscirpenol produced by Fusarium sambucinum cultures isolated from potato tubers and their toxicity to brine shrimps (Artemia salina). Mycotoxin Res. 5(2), 61-67 (1989).

    4. Ayral, A.M., Dubech, N., Le Bars, J., et al. In vitro effect of diacetoxyscirpenol and deoxynivalenol on microbicidal activity of murine peritoneal macrophages. Mycopathologia 120(2), 121-127 (1992).

    5. Hasan, H.A. Phytotoxicity of pathogenic fungi and their mycotoxins to cereal seedling viability. Mycopathologia 148(3), 149-155 (1999).

    6. Kononenko, G.P., Burkin, A.A., Gavrilova, O.P., et al. Fungal species and multiple mycotoxin contamination of cultivated forage crops. Agric. Food Sci. 24(4), 323-330 (2015).