A trichothecene mycotoxin
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15-acetoxy Scirpenol

Item No. 11431

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
12,13-epoxy-trichothec-9-ene-3α,4β,15-triol, 15-acetate
CAS Number
2623-22-5
Synonyms
  • 4-Deacetylanguidin
  • NSC 267030
Molecular Formula
C17H24O6
Formula Weight
324.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:4): 0.2 mg/mlDMSO: 30 mg/mlEthanol: 20 mg/ml
SMILES
CC1=C[C@]2([H])[C@]([C@]([C@H](O)[C@H]3O)(C)[C@@]4(OC4)[C@]3([H])O2)(COC(C)=O)CC1
InChi Code
InChI=1S/C17H24O6/c1-9-4-5-16(7-21-10(2)18)11(6-9)23-14-12(19)13(20)15(16,3)17(14)8-22-17/h6,11-14,19-20H,4-5,7-8H2,1-3H3/t11-,12-,13-,14-,15-,16-,17+/m1/s1
InChi Key
IRXDUBNENLKYTC-OINWIYPRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Cayman Chemical
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    Product Description

    15-acetoxy Scirpenol is a trichothecene mycotoxin that is produced predominantly by members of the Fusarium genus.1 It can induce apoptotic cell death in human Jurkat T cells.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Peraica, M., Radić, B., Lucić, A., et al. Toxic effects of mycotoxins in humans. Bull. World Health Ogan. 77(9), 754-766 (1999).

    2. Lee, D.H., Park, T., and Kim, H.W. Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxins. Biol. Pharm. Bull. 29(4), 648-654 (2006).