A type B trichothecene mycotoxin
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Product Type

Environmental Toxicology
Toxins
Mycotoxins

Fusarenon X

Item No. 11432

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4β-(acetyloxy)-12,13-epoxy-3α,7α,15-trihydroxy-trichothec-9-en-8-one
CAS Number
23255-69-8
Synonyms
  • 4-acetyl Nivalenol
  • NSC 197211
Molecular Formula
C17H22O8
Formula Weight
354.4
Purity
≥99%
Formulation
A 500 µg/ml solution in dichloromethane
Solubility(Learn about Variance in Solubility)
Dichloromethane: Soluble
SMILES
CC1=C[C@]2([H])[C@]([C@]([C@H](OC(C)=O)[C@H]3O)(C)[C@@]4(OC4)[C@]3([H])O2)(CO)[C@H](O)C1=O
InChi Code
InChI=1S/C17H22O8/c1-7-4-9-16(5-18,12(22)10(7)20)15(3)13(24-8(2)19)11(21)14(25-9)17(15)6-23-17/h4,9,11-14,18,21-22H,5-6H2,1-3H3/t9-,11-,12-,13-,14-,15-,16-,17+/m1/s1
InChi Key
XGCUCFKWVIWWNW-CAYGJDLQSA-N
Origin
Fungus/Fusarium sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Fusarenon X is a type B trichothecene mycotoxin typically derived from Fusarium species. It is primarily found in contaminated cereals.1 Fusarenon X inhibits protein synthesis, which leads to disruption of DNA synthesis.1 As this occurs in actively proliferating cells, fusarenon X causes immunosuppression, intestinal malabsorption, developmental toxicity, and genotoxicity.1 Fusarenon X can be metabolized to fusarenon X-glucoside by infected plants.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aupanun, S., Poapolathep, S., Girogi, M., et al. An overview of the toxicology and toxicokinetics of fusarenon-X, a type B trichothecene mycotoxin. J. Vet. Med. Sci. 79(11), 6-13 (2016).

    2. Berthiller, F., Crews, C., Dall'Asta, C., et al. Masked mycotoxins: A review. Mol. Nutr. Food Res. 57(1), 165-186 (2013).