A pentacyclic triterpene
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α-acetyl Boswellic Acid

Item No. 11673

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3α,4β)-3-(acetyloxy)-olean-12-en-23-oic acid
CAS Number
89913-60-0
Synonyms
  • ABA
  • 3-O-acetyl-α-Boswellic Acid
  • α-Boswellic Acid Acetate
Molecular Formula
C32H50O4
Formula Weight
498.7
Purity
≥99%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 5 mg/ml
SMILES
CC1(C)CC[C@]2(C)CC[C@@]3(C)[C@@]4(C)[C@]([C@](CC[C@@H](OC(C)=O)[C@@]5(C(O)=O)C)(C)[C@@]5([H])CC4)([H])CC=C3[C@]2([H])C1
InChi Code
InChI=1S/C32H50O4/c1-20(33)36-25-12-13-29(5)23-10-9-21-22-19-27(2,3)15-16-28(22,4)17-18-30(21,6)31(23,7)14-11-24(29)32(25,8)26(34)35/h9,22-25H,10-19H2,1-8H3,(H,34,35)/t22-,23+,24+,25+,28+,29+,30+,31+,32?/m0/s1
InChi Key
IAWGZKRQDHPFCZ-KUZXTENQSA-N
Origin
Plant/Boswellia serrata
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $103

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    5 mg

    $378

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    10 mg

    $553

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    Product Description

    α-acetyl Boswellic acid is a pentacyclic triterpene and isomer of β-acetyl-boswellic acid (Item No. 11674) originally isolated from B. serrata.1 It inhibits LPS-induced TNF-α mRNA expression in monocytes as well as NF-κB activity in HEK293 cells when used at a concentration of 10 μM.1 α-acetyl Boswellic acid also inhibits phosphorylation of IκBα mediated by IκB kinases (IKKs) in monocytes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Syrovets, T., Büchele, B., Krauss, C., et al. Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-α induction in monocytes by direct interaction with IκB kinases. J. Immunol. 174(1), 498-506 (2005).