A CYP450 inhibitor
Related Products
Isomer(s)
39246Anthraflavic Acid
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Alizarin

Item No. 11676

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,2-dihydroxy-9,10-anthracenedione
CAS Number
72-48-0
Synonyms
  • CI-58000
  • NSC 7212
Molecular Formula
C14H8O4
Formula Weight
240.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/mlEthanol: Slightly soluble
λmax
248, 433 nm
SMILES
O=C1C2=C(C(O)=C(O)C=C2)C(C3=C1C=CC=C3)=O
InChi Code
InChI=1S/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18H
InChi Key
RGCKGOZRHPZPFP-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 g

    $36

    Add

    100 g

    $55

    Add

    250 g

    $128

    Add
    Product Description

    Alizarin is a small molecule inhibitor of cytochrome P450 isoforms CYP1A1, CYP1A2, and CYP1B1 (IC50s = 6.2, 10, and 2.7 µM, respectively).1 Alizarin acts as an antioxidant against iodophenol-derived phenoxyl radicals, superoxide anion radicals, and lipid peroxidation in rat liver microsomes.2 It also reduces hepatic content of thiobarbituric acid-reactive substances and serum levels of alanine aminotransferase in poisoned rats.2 Alizarin is also used as a red dye to stain bacteria, human adipose-derived stem cells, multipotent adult progenitor cells, skin, hair, and keratin fibers.3,4,5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chin, C.L., Tovcimak, A.E., Hradil, V.P., et al. Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI. Br. J. Pharmacol. 153(2), 367-379 (2008).

    2. Kumar, B.M., Yoo, J.-G., Ock, S.A., et al. In vitro differentiation of mesenchymal progenitor cells derived from porcine umbilical cord blood. Mol. Cells. 24(3), 343-350 (2007).

    3. Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010).

    4. Louvet, O., Thualt, D., and Vaillant, R. Method and device for determining if a product is in condition for use or consumption. (2005).

    5. Dumosseaux, C. Composition for use on the skin, lips and/or nails. (2005).