A pentacyclic triterpene
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Isomer(s)
11693β-Boswellic Acid
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α-Boswellic Acid

Item No. 11692

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4β)-3α-hydroxy-olean-12-en-23-oic acid
CAS Number
471-66-9
Molecular Formula
C30H48O3
Formula Weight
456.7
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlDMSO:PBS (pH 7.2) (1:2): 0.30 mg/mlEthanol: 5 mg/ml
SMILES
O[C@@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC=C4[C@@]3(C)CC[C@]5(C)[C@@]4([H])CC(C)(C)CC5)([H])[C@]1(C(O)=O)C
InChi Code
InChI=1S/C30H48O3/c1-25(2)14-15-26(3)16-17-28(5)19(20(26)18-25)8-9-21-27(4)12-11-23(31)30(7,24(32)33)22(27)10-13-29(21,28)6/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21+,22+,23+,26+,27+,28+,29+,30?/m0/s1
InChi Key
BZXULBWGROURAF-LDWVVYRUSA-N
Origin
Plant/Boswellia carterii
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    10 mg

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    Product Description

    α-Boswellic acid is a pentacyclic triterpene and an isomer of β-boswellic acid (Item No. 11693) originally isolated from B. serrata.1,2 It increases Survivin and Reelin expression, decreases production of reactive oxygen species (ROS) and levels of hyperphosphorylated Tau, and inhibits apoptosis induced by streptozotocin (Item No. 13104) in primary fetal human astrocytes.1 α-Boswellic acid (200 mg/kg) increases gastric juice pH and production of gastric wall mucus and decreases leukocyte infiltration, submucosal edema, and the formation of hemorrhagic lesions in a rat model of ethanol-induced gastric injury.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fathi, E., Katouli, F.H., Riazi, G.H., et al. The effects of alpha boswellic acid on reelin expression and Tau phosphorylation in human astrocytes. Neuromolecular Med. 19(1), 136-146 (2017).

    2. Zhang, Y., Jia, J., Ding, Y., et al. Alpha-boswellic acid protects against ethanol-induced gastric injury in rats: Involvement of nuclear factor erythroid-2-related factor 2/heme oxygenase-1 pathway. J. Pharm. Pharmacol. 68(4), 514-522 (2016).