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Labeled Version(s)
9001493Benocyclidine-d10
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Benocyclidine

Item No. 11737

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • BCP
  • Benzothiophenylcyclohexylpiperidine
  • BTCP
  • GK 13
Technical Information
Formal Name
1-(1-benzo[b]thien-2-ylcyclohexyl)-piperidine
CAS Number
112726-66-6
Molecular Formula
C19H25NS
Formula Weight
299.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlEthanol: 2 mg/ml
λmax
229, 270, 300 nm
SMILES
N1(CCCCC1)C2(C3=CC(C=CC=C4)=C4S3)CCCCC2
InChi Code
InChI=1S/C19H25NS/c1-5-11-19(12-6-1,20-13-7-2-8-14-20)18-15-16-9-3-4-10-17(16)21-18/h3-4,9-10,15H,1-2,5-8,11-14H2
InChi Key
RGSVXQJPSWZXOP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Benzocyclidine (BCP) is a derivative of phencyclidine with a benzothiophenyl group instead of a phenyl ring. It acts as a potent and selective dopamine reuptake inhibitor (IC50 = 8 nM) with negligible affinity for the NMDA receptor-linked phencyclidine receptor (K0.5 = 6 μM).1,2 BCP has been used to label the dopamine transporter in the mouse brain.3 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vignon, J., Pinet, V., Cerruti, C., et al. [3H]N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine ([3H]BTCP): A new phencyclidine analog selective for the dopamine uptake complex. Eur. J. Pharmacol. 148(3), 427-436 (1988).

    2. Chaudieu, I., Vignon, J., Chicheportiche, M., et al. Role of the aromatic group in the inhibition of phencyclidine binding and dopamine uptake by PCP analogs. Pharmacol. Biochem. Behav. 32(3), 699-705 (1989).

    3. Maurice, T., Vignon, J., Kamenka, J.M., et al. In vivo labelling of the mouse dopamine uptake complex with the phencyclidine derivative [3H]BTCP. Neurosci. Lett. 101(2), 234-238 (1989).